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Experimental approach for <t>fMRI</t> during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.
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Experimental approach for <t>fMRI</t> during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.
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Experimental approach for <t>fMRI</t> during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.
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Experimental approach for <t>fMRI</t> during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.
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Experimental approach for <t>fMRI</t> during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.
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Image Search Results


Experimental approach for fMRI during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.

Journal: CNS Neuroscience & Therapeutics

Article Title: Functional MRI Analysis of Brain Activity in Rats With Diabetic Bladder Dysfunction

doi: 10.1111/cns.70466

Figure Lengend Snippet: Experimental approach for fMRI during Reflexive Micturition. (a) This task‐related fMRI sequence began with an empty bladder, and MRI scanning was performed for two cycles as “Empty”. Then, the bladder infusion started. When stable bladder contractions were observed, MRI scanning was conducted for two cycles as “Infusion.” Next, MRI paused, and NLX‐112 (0.3 g/kg) was injected through the jugular vein. MRI scanning was performed for two cycles as “after – drugs.” Finally, MRI and infusion stopped. (b) The “Infusion” period was divided into the contraction period and the relaxation period by cystometric methods, and MRI images were divided into task‐fMRI and rs‐fMRI.

Article Snippet: Finally, 12 NC rats and 12 DM rats were included in the comparative analysis of rs‐fMRI. fMRI data were preprocessed using Statistical Parametric Mapping (SPM12, Wellcome Trust Centre for Neuroimaging) and Data Processing Assistant for Resting‐State fMRI (DPARSF) on MATLAB R2014b.

Techniques: Sequencing, Injection